heparan sulfate การใช้

• Differential heparan sulfate chain modification can occur through a number of regulatory signals.
• These bindings site can bind copper, zinc, collagen and heparan sulfate.
• This enzyme participates in heparan sulfate biosynthesis and glycan structures-biosynthesis 1.
• Heparan sulfate interacts with both of these clusters.
• It is a component of dermatan sulfate and heparan sulfate, which are glycosaminoglycans.
• This releases growth factors bound to the heparan sulfate, specifically FGF-10.
• It also cleaves chondroitin sulfate, heparan sulfate and proteoglycans of the basal membrane.
• Instead, MBP recognises heparan sulfate proteoglycans.
• It consists of a mixture of heparan sulfate, dermatan sulfate, and chondroitin sulfate.
• It is involved in the degeneration of glycosaminoglycans such as dermatan sulfate and heparan sulfate.
• This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.
• Loss of enzymes involved in the heparan sulfate synthetic pathway lead to a number of conditions.
• The mechanism by which heparan sulfate was downregulated in these lesions remained unknown for some time.
• Iduronate 2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate.
• Research into Pipe's catalytic activity eliminated the likelihood of it being a heparan sulfate glycosaminoglycan.
• Syndecan-1 is a sponge for growth factors, with binding largely via heparan sulfate chains.
• Heparan sulfate proteoglycans ( HSPGs ) are widely expressed throughout most tissues of nearly all multicellular species.
• Pipe is currently classified as a " Drosophilia " heparan sulfate 2-O-sulfotransferase.
• This article states that heparanase is responsible for cleavage of the heparan sulfate chains of perlecan in matrix.
• This deletion abolished heparan sulfate chain attachment to the resulting core protein " in vivo ".